Follicle-stimulating hormone (FSH), secreted by the anterior pituitary, is a critical regulator of female reproductive physiology. Its main physiological function is to promote follicle development and estrogen secretion, while also participating in the formation of normal menstruation, which is of great significance for female fertility. In the early follicular phase, rising FSH initiates follicular recruitment. Consequently, basal FSH measured on cycle days 2–4 is widely used in clinical practice to assess ovarian function and ovarian reserve.
Clinical Interpretation of FSH (per ASRM Guidelines)
- Normal range: typically <10 IU/L
- Caution zone: 10–15 IU/L suggests diminishing ovarian function
- Diagnostic threshold: persistent FSH>25 IU/L in a young woman, accompanied by menstrual irregularity, raises concern for premature ovarian insufficiency (POI)
FSH must always be interpreted in conjunction with AMH, antral follicle count (AFC), and chronological age. Isolated values should be viewed with caution.
Scientific Cognition and Action Recommendations
To correctly understand the FSH indicator, the following points need to be clarified:
- FSH is a dynamically changing monitoring indicator
- Results need to be interpreted by a professional physician considering multiple factors
- Individualized treatment plans are crucial
Recommended actions upon identification of elevated FSH:
- Consultation with a reproductive endocrinologist
- Comprehensive fertility evaluation
- Development of a personalised management plan
- Consideration of physician-guided adjunctive therapies
Management Strategies When FSH Indicates Reduced Ovarian Function
Contemporary reproductive medicine employs an integrated approach aimed at optimising the follicular microenvironment and oocyte quality:
- Lifestyle optimisation of lifestyle factors
- Evidence-based nutritional support
- Medical intervention when indicated
Within this framework, scientifically validated nutritional supplements can be used as an adjunct option. For example, Juvenex Reco18‘s core ingredient, Reco18, synergistically improves the ovarian microenvironment through multiple pathways: it promotes granulosa cell proliferation, inhibits apoptosis, and enhances the efficiency of FSH signaling by upregulating the gene and protein expression of FSH receptors in ovarian tissue. This is equivalent to enhancing the ovary’s responsiveness to FSH at the molecular level, optimizing the microenvironment and hormonal support for follicle development, thereby improving the maturation quality and developmental potential of oocytes.
This product has passed FDA registration, ISO quality system certification, and SGS hormone testing. It is free of hormones, heavy metals, and harmful ingredients, meeting food safety standards.
Summary
FSH remains a cornerstone biomarker for evaluating ovarian reserve and ovarian function. Through systematic testing, expert interpretation, and structured management, age-related changes in ovarian function can be effectively addressed. Under specialist guidance, evidence-based adjunctive measures such as Juvenex Reco18 can provide targeted nutritional support for follicular health and development.
