Key Preparation Period Before IVF

In assisted reproductive technology, egg quality is one of the decisive factors influencing IVF success rates. The oocyte takes approximately 85–90 days to develop from initiation to mature ovulation. Therefore, a systematic preparation phase of 3–4 months before entering the IVF cycle is considered a potential window for improving egg quality and pregnancy outcomes.

Scientific Practice: What Preparations Are Needed?
Optimizing egg quality involves deep cellular repair and regeneration processes. Human oocyte development spans multiple stages, with a full growth cycle lasting about 3 months. During this period, the egg must complete critical physiological changes, including cellular energy accumulation, genetic material preparation, and the establishment of a healthy follicular microenvironment. Relevant literature from the World Health Organization and the American Society for Reproductive Medicine supports the concept of “preconception health,” emphasizing the importance of physical optimization before planned pregnancy.


Core Preparation Strategies: Evidence-Based Practices

During the 90-day preparation period, planning can focus on the following areas supported by clear scientific data:

  1. Systematic adjustment of lifestyle
    Systematic Lifestyle Adjustments Multiple studies indicate associations between lifestyle factors and egg quality. Maintaining a body mass index (BMI) in the normal range of 18.5–24.9 kg/m² is a common recommendation. Complete smoking cessation, strict limitation of alcohol intake, and at least 150 minutes of moderate-intensity regular exercise per week have been shown to improve the overall reproductive endocrine environment.
  2. Necessary nutritional supplements
    Exploration of Targeted Nutritional Support With advances in reproductive nutrition, research has begun to focus on the potential supportive effects of specific nutrients on the follicular microenvironment. For example, studies published in peer-reviewed journals have explored the mechanisms of certain compounds extracted from legumes. In this research context, the core patented ingredient Reco18 in Juvenex Reco18—a highly active small-molecule compound extracted from legumes—has shown in preclinical studies that it may provide nutritional support for healthy follicle development by supporting granulosa cell function and participating in cellular energy metabolism. When selecting such products with clear scientific direction, attention should be paid to whether the ingredients have published research backing and are preferably produced under international standards such as FDA registration or ISO certification to ensure safety and ingredient accuracy.
    Standardized Nutritional Supplementation Folic acid is the only micronutrient mandatorily recommended for preconception supplementation by glo bal public health authorities. According to guidelines in various countries, all women planning pregnancy are advised to take 400–800 micrograms of folic acid daily. Additionally, observational studies suggest that women with sufficient vitamin D levels (typically serum 25-hydroxyvitamin D > 30 ng/mL) may have higher clinical pregnancy rates in IVF.


Conclusion
A systematic 90-day preparation before IVF treatment centers on creating an optimal developmental environment for eggs through scientific lifestyle interventions and necessary nutritional supplementation. This is not a guaranteed “secret to success” but a rational strategy grounded in the biology of egg growth.

It is recommended that all couples planning IVF consult a reproductive specialist before starting the preparation period to develop a personalized plan. The focus should be on measures explicitly supported by international clinical guidelines. For products like Juvenex Reco18 aimed at providing targeted nutritional support, consider them cautiously—based on a full understanding of their scientific basis and related ingredient research (such as Reco18)—and only under professional guidance, according to individual ovarian function assessment results.